Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias

Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show considerable promise for regenerating injured hearts, and we therefore tested their capacity to stably engraft in a translationally relevant preclinical model, the infarcted pig heart. Transplantation of immature hESC-CMs resulted in s...

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Detalles Bibliográficos
Autores principales: Romagnuolo, Rocco, Masoudpour, Hassan, Porta-Sánchez, Andreu, Qiang, Beiping, Barry, Jennifer, Laskary, Andrew, Qi, Xiuling, Massé, Stéphane, Magtibay, Karl, Kawajiri, Hiroyuki, Wu, Jun, Valdman Sadikov, Tamilla, Rothberg, Janet, Panchalingam, Krishna M., Titus, Emily, Li, Ren-Ke, Zandstra, Peter W., Wright, Graham A., Nanthakumar, Kumaraswamy, Ghugre, Nilesh R., Keller, Gordon, Laflamme, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524945/
https://www.ncbi.nlm.nih.gov/pubmed/31056479
http://dx.doi.org/10.1016/j.stemcr.2019.04.005

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