Cargando…

A terpene synthase-cytochrome P450 cluster in Dictyostelium discoideum produces a novel trisnorsesquiterpene

Terpenoids are enormously diverse, but our knowledge of their biosynthesis and functions is limited. Here we report on a terpene synthase (DdTPS8)-cytochrome P450 (CYP521A1) gene cluster that produces a novel C12 trisnorsesquiterpene and affects the development of Dictyostelium discoideum. DdTPS8 ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xinlu, Luck, Katrin, Rabe, Patrick, Dinh, Christopher QD, Shaulsky, Gad, Nelson, David R, Gershenzon, Jonathan, Dickschat, Jeroen S, Köllner, Tobias G, Chen, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524965/ https://www.ncbi.nlm.nih.gov/pubmed/31063135 http://dx.doi.org/10.7554/eLife.44352

Ejemplares similares

Diversity and Functional Evolution of Terpene Synthases in Dictyostelid Social Amoebae
por: Chen, Xinlu, et al.
Publicado: (2018)

Cooperative predation in the social amoebae Dictyostelium discoideum
por: Rubin, Michelle, et al.
Publicado: (2019)

Cheating by Exploitation of Developmental Prestalk Patterning in Dictyostelium discoideum
por: Khare, Anupama, et al.
Publicado: (2010)

ABC Transporters in Dictyostelium discoideum Development
por: Miranda, Edward Roshan, et al.
Publicado: (2013)

The Long Noncoding RNA Transcriptome of Dictyostelium discoideum Development
por: Rosengarten, Rafael D., et al.
Publicado: (2016)

Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum
por: Rosengarten, Rafael David, et al.
Publicado: (2015)

A new social gene in Dictyostelium discoideum, chtB
por: Santorelli, Lorenzo A, et al.
Publicado: (2013)

The reconstruction and biochemical characterization of ancestral genes furnish insights into the evolution of terpene synthase function in the Poaceae
por: Luck, Katrin, et al.
Publicado: (2020)

Terpene Synthase Genes Originated from Bacteria through Horizontal Gene Transfer Contribute to Terpenoid Diversity in Fungi
por: Jia, Qidong, et al.
Publicado: (2019)

Curcumin affects gene expression and reactive oxygen species via a PKA dependent mechanism in Dictyostelium discoideum
por: Swatson, William S., et al.
Publicado: (2017)

Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
por: Sucgang, Richard, et al.
Publicado: (2011)

Evolution of isoprenyl diphosphate synthase-like terpene synthases in fungi
por: Wei, Guo, et al.
Publicado: (2020)

Data on the expression and purification of Sestrin protein from Dictyostelium discoideum
por: Rafia, S., et al.
Publicado: (2019)

dictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface
por: Rot, Gregor, et al.
Publicado: (2009)

Origin and early evolution of the plant terpene synthase family
por: Jia, Qidongs, et al.
Publicado: (2022)

Mapping and characterization of G-quadruplexes in the genome of the social amoeba Dictyostelium discoideum
por: Saad, Mona, et al.
Publicado: (2019)

The organ-specific expression of terpene synthase genes contributes to the terpene hydrocarbon composition of chamomile essential oils
por: Irmisch, Sandra, et al.
Publicado: (2012)

Motility mutants of Dictyostelium discoideum
Publicado: (1982)

In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases
por: Sutherland, Molly C, et al.
Publicado: (2021)

Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats
por: Xu, Shang-Fu, et al.
Publicado: (2019)

The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum
por: Gonzalez-Kristeller, Daniela C, et al.
Publicado: (2008)

Mechanistic investigations on six bacterial terpene cyclases
por: Rabe, Patrick, et al.
Publicado: (2016)

Dictyostelium Discoideum: A Developmental System
por: Zeldis, Jerome B.
Publicado: (1976)

Selection of chemotaxis mutants of Dictyostelium discoideum
Publicado: (1987)

Spindle and kinetochore morphology of Dictyostelium discoideum
Publicado: (1976)

Prelysosomal acidic vacuoles in Dictyostelium discoideum
Publicado: (1989)

Centromere sequence and dynamics in Dictyostelium discoideum
por: Glöckner, Gernot, et al.
Publicado: (2009)

Retrotransposon Domestication and Control in Dictyostelium discoideum
por: Malicki, Marek, et al.
Publicado: (2017)

Spontaneous center formation in Dictyostelium discoideum
por: Vidal-Henriquez, Estefania, et al.
Publicado: (2019)

Modifications of lysosomal enzymes in Dictyostelium discoideum
por: Freeze, Hudson H.
Publicado: (1986)

Will 1,2-dihydro-1,2-azaborine-based drugs resist metabolism by cytochrome P450 compound I?
por: Silva, Pedro J.
Publicado: (2016)

Functional expression and purification of DoxA, a key cytochrome P450 from Streptomyces peucetius ATCC 27952
por: Yang, Liyan, et al.
Publicado: (2022)

Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase
por: Besskaya, Valeria, et al.
Publicado: (2023)

Terpenes
por: Dickschat, Jeroen S
Publicado: (2019)

Terpene synthases and their contribution to herbivore-induced volatile emission in western balsam poplar (Populus trichocarpa)
por: Irmisch, Sandra, et al.
Publicado: (2014)

TgrC1 Has Distinct Functions in Dictyostelium Development and Allorecognition
por: Wang, Yue, et al.
Publicado: (2015)

Enzymatic Synthesis of Methylated Terpene Analogues Using the Plasticity of Bacterial Terpene Synthases
por: Hou, Anwei, et al.
Publicado: (2020)

Dictyostelium discoideum mutants with conditional defects in phagocytosis
Publicado: (1994)

Subcellular localization of ammonium transporters in Dictyostelium discoideum
por: Kirsten, Janet H, et al.
Publicado: (2008)

Resistance of Dictyostelium discoideum membranes to saponin permeabilization
por: Mercanti, Valentina, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_07dnconfu2l8guobr2dpdh5o7h