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Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle

During the asymmetric divisions of Drosophila neuroblasts, the Par polarity complex cycles between the cytoplasm and an apical cortical domain that restricts differentiation factors to the basal cortex. We used rapid imaging of the full cell volume to uncover the dynamic steps that underlie transiti...

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Detalles Bibliográficos
Autores principales: Oon, Chet Huan, Prehoda, Kenneth E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524966/
https://www.ncbi.nlm.nih.gov/pubmed/31066675
http://dx.doi.org/10.7554/eLife.45815