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Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo

Definitive hematopoietic stem cells (HSCs) first emerge in the aorta-gonad-mesonephros (AGM) region in both mice and humans. An ex vivo culture approach has enabled recapitulation and analysis of murine HSC development. Knowledge of early human HSC development is hampered by scarcity of tissue: anal...

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Detalles Bibliográficos
Autores principales:	Easterbrook, Jennifer, Rybtsov, Stanislav, Gordon-Keylock, Sabrina, Ivanovs, Andrejs, Taoudi, Samir, Anderson, Richard A., Medvinsky, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525107/ https://www.ncbi.nlm.nih.gov/pubmed/30956115 http://dx.doi.org/10.1016/j.stemcr.2019.03.003

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