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Pharmacokinetics of S-1 monotherapy in plasma and in tears for gastric cancer patients

BACKGROUND: S-1 is an oral anticancer drug composed of tegafur (FT), which is a prodrug of 5-FU, 5-chloro-2,4-dihydroxypyridine (CDHP), and potassium oxonate. Recently, some studies have been reported on watering eyes caused by S-1. However, the mechanism of watering eyes caused by S-1 is still uncl...

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Detalles Bibliográficos
Autores principales:	Yasui, Hirofumi, Kawakami, Takeshi, Kashiwagi, Hiroya, Mori, Keita, Omae, Katsuhiro, Kasai, Jun, Yoshisue, Kunihiro, Kawahira, Masahiro, Tsushima, Takahiro, Machida, Nozomu, Fukutomi, Akira, Yamaguchi, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525142/ https://www.ncbi.nlm.nih.gov/pubmed/31011915 http://dx.doi.org/10.1007/s10147-018-01387-6

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