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Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells
Variants of triggering receptor expressed on myeloid cells 2 (TREM2) are associated with an increased incidence of Alzheimer’s disease, as well as other neurodegenerative disorders. Using a newly developed, highly sensitive reporter cell model, consisting of Jurkat T cells stably overexpressing a re...
Autores principales: | Shirotani, Keiro, Hori, Yuma, Yoshizaki, Ryohei, Higuchi, Eri, Colonna, Marco, Saito, Takashi, Hashimoto, Shoko, Saido, Takaomi C., Iwata, Nobuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525155/ https://www.ncbi.nlm.nih.gov/pubmed/31101881 http://dx.doi.org/10.1038/s41598-019-43535-6 |
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