Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8(+) effector recruitment to mucosal tissues

CD8(+) T cells provide a critical defence from pathogens at mucosal epithelia including the female reproductive tract (FRT). Mucosal immunisation is considered essential to initiate this response, however this is difficult to reconcile with evidence that antigen delivered to skin can recruit protect...

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Detalles Bibliográficos
Autores principales: Zaric, Marija, Becker, Pablo D., Hervouet, Catherine, Kalcheva, Petya, Doszpoly, Andor, Blattman, Negin, A. O’ Neill, Lauren, Yus, Barbara Ibarzo, Cocita, Clement, Kwon, Sung-Yun, Baker, Andrew H., Lord, Graham M., Klavinskis, Linda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525176/
https://www.ncbi.nlm.nih.gov/pubmed/31101810
http://dx.doi.org/10.1038/s41467-019-09969-2

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