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Suppression of R5-type of HIV-1 in CD4(+) NKT cells by Vδ1(+) T cells activated by flavonoid glycosides, hesperidin and linarin

We established transfectants expressing T cell receptors (TCRs) either for Vγ1 and Vδ1 (1C116) or for Vγ2 and Vδ2 (2C21) using the TCR-deficient Jurkat T cell line J.RT3-T3.5. The amount of IL-2 secreted from these γδ T cell clones accurately indicated TCR-dependent stimulation. Clone 2C21 was speci...

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Detalles Bibliográficos
Autores principales: Yonekawa, Michiyuki, Shimizu, Masumi, Kaneko, Atsushi, Matsumura, Jiro, Takahashi, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525194/
https://www.ncbi.nlm.nih.gov/pubmed/31101837
http://dx.doi.org/10.1038/s41598-019-40587-6

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