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In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release

Transcribing and replicating a double-stranded genome require protein modules to unwind, transcribe/replicate nucleic acid substrates, and release products. Here we present in situ cryo-electron microscopy structures of rotavirus dsRNA-dependent RNA polymerase (RdRp) in two states pertaining to tran...

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Detalles Bibliográficos
Autores principales:	Ding, Ke, Celma, Cristina C., Zhang, Xing, Chang, Thomas, Shen, Wesley, Atanasov, Ivo, Roy, Polly, Zhou, Z. Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525196/ https://www.ncbi.nlm.nih.gov/pubmed/31101900 http://dx.doi.org/10.1038/s41467-019-10236-7

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