The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

The tamoxifen-responsive conditional Cdh5-CreERT2 is commonly used for endothelial cell specific conditional deletion of loxP-flanked gene sequences. To address the role of endothelial cell Shb gene for B16F10 melanoma immune responses, tamoxifen-injected Cdh5-CreERT2/WT and Cdh5-CreERT2/Shb(flox/fl...

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Detalles Bibliográficos
Autores principales: He, Qi, Li, Xiujuan, Singh, Kailash, Luo, Zhengkang, Meija-Cordova, Mariela, Jamalpour, Maria, Lindahl, Björn, Kriz, Vitezslav, Vuolteenaho, Reetta, Ulvmar, Maria, Welsh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525206/
https://www.ncbi.nlm.nih.gov/pubmed/31101877
http://dx.doi.org/10.1038/s41598-019-44039-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525206/
https://www.ncbi.nlm.nih.gov/pubmed/31101877
http://dx.doi.org/10.1038/s41598-019-44039-z

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