Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are recruited to the cortex by Gαi-sub...

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Detalles Bibliográficos
Autores principales: Pirovano, Laura, Culurgioni, Simone, Carminati, Manuel, Alfieri, Andrea, Monzani, Silvia, Cecatiello, Valentina, Gaddoni, Chiara, Rizzelli, Francesca, Foadi, James, Pasqualato, Sebastiano, Mapelli, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525239/
https://www.ncbi.nlm.nih.gov/pubmed/31101817
http://dx.doi.org/10.1038/s41467-019-09999-w

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