Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis

Cell surface β-Amyloid precursor protein (APP) is known to have a functional role in iron homeostasis through stabilising the iron export protein ferroportin (FPN). Mechanistic evidence of this role has previously only been provided through transcriptional or translational depletion of total APP lev...

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Detalles Bibliográficos
Autores principales: Tsatsanis, Andrew, Dickens, Stuart, Kwok, Jessica C. F., Wong, Bruce X., Duce, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525264/
https://www.ncbi.nlm.nih.gov/pubmed/30796750
http://dx.doi.org/10.1007/s11064-019-02747-y

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