Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients

TAVR has become the standard treatment in patients at increased surgical risk (STS or EuroSCORE II ≥4% or logistic EuroSCORE I ≥ 10% or other risk factors not included in these scores such as frailty, porcelain aorta, sequelae of chest radiation) and it is increasingly being performed in patients at...

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Autores principales: Ielasi, Alfonso, Latib, Azeem, Tespili, Maurizio, Donatelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525308/
https://www.ncbi.nlm.nih.gov/pubmed/31193348
http://dx.doi.org/10.1016/j.ijcha.2019.100375
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author Ielasi, Alfonso
Latib, Azeem
Tespili, Maurizio
Donatelli, Francesco
author_facet Ielasi, Alfonso
Latib, Azeem
Tespili, Maurizio
Donatelli, Francesco
author_sort Ielasi, Alfonso
collection PubMed
description TAVR has become the standard treatment in patients at increased surgical risk (STS or EuroSCORE II ≥4% or logistic EuroSCORE I ≥ 10% or other risk factors not included in these scores such as frailty, porcelain aorta, sequelae of chest radiation) and it is increasingly being performed in patients at intermediate to low (STS or EuroSCORE II <4% or logistic EuroSCORE I < 10%) surgical risk. Although non-inferiority has been demonstrated in intermediate and low-risk patients, several challenges need to be addressed before expansion to younger patients. Current trends, trials results, and remaining challenges are summarized and discussed in this review.
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spelling pubmed-65253082019-05-28 Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients Ielasi, Alfonso Latib, Azeem Tespili, Maurizio Donatelli, Francesco Int J Cardiol Heart Vasc Review TAVR has become the standard treatment in patients at increased surgical risk (STS or EuroSCORE II ≥4% or logistic EuroSCORE I ≥ 10% or other risk factors not included in these scores such as frailty, porcelain aorta, sequelae of chest radiation) and it is increasingly being performed in patients at intermediate to low (STS or EuroSCORE II <4% or logistic EuroSCORE I < 10%) surgical risk. Although non-inferiority has been demonstrated in intermediate and low-risk patients, several challenges need to be addressed before expansion to younger patients. Current trends, trials results, and remaining challenges are summarized and discussed in this review. Elsevier 2019-05-15 /pmc/articles/PMC6525308/ /pubmed/31193348 http://dx.doi.org/10.1016/j.ijcha.2019.100375 Text en © 2019 Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Ielasi, Alfonso
Latib, Azeem
Tespili, Maurizio
Donatelli, Francesco
Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
title Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
title_full Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
title_fullStr Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
title_full_unstemmed Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
title_short Current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
title_sort current results and remaining challenges of trans-catheter aortic valve replacement expansion in intermediate and low risk patients
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525308/
https://www.ncbi.nlm.nih.gov/pubmed/31193348
http://dx.doi.org/10.1016/j.ijcha.2019.100375
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