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Determination of tobacco alkaloid enantiomers using reversed phase UPLC/MS/MS

Nʹ-Nitrosonornicotine (NNN), a carcinogenic tobacco-specific Nʹ-nitrosamine (TSNA), is on the FDA list of harmful and potentially harmful constituents (HPHCs). Nornicotine, a product of the demethylation of nicotine, is the immediate alkaloid precursor for NNN formation. Nicotine, nornicotine and NN...

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Detalles Bibliográficos
Autores principales: Ji, Huihua, Wu, Ying, Fannin, Franklin, Bush, Lowell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525314/
https://www.ncbi.nlm.nih.gov/pubmed/31193304
http://dx.doi.org/10.1016/j.heliyon.2019.e01719