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Perturbational Gene-Expression Signatures for Combinatorial Drug Discovery
Cancer is a complex disease that relies on both oncogenic mutations and non-mutated genes for survival, and therefore coined as oncogene and non-oncogene addictions. The need for more effective combination therapies to overcome drug resistance in oncology has been increasingly recognized, but the id...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525321/ https://www.ncbi.nlm.nih.gov/pubmed/31102995 http://dx.doi.org/10.1016/j.isci.2019.04.039 |