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Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren’s syndrome

BACKGROUND: Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide hypocretin-1 (Hcrt1), a regulator of wakefulness, influence fatigue. METHODS: H...

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Detalles Bibliográficos
Autores principales:	Bårdsen, Kjetil, Brede, Cato, Kvivik, Ingeborg, Kvaløy, Jan Terje, Jonsdottir, Kristin, Tjensvoll, Anne Bolette, Ruoff, Peter, Omdal, Roald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525358/ https://www.ncbi.nlm.nih.gov/pubmed/31101054 http://dx.doi.org/10.1186/s12974-019-1502-8

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