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Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization

BACKGROUND: Nicotinamide N-methyltransferase (NNMT) is overexpressed in various human tumors and involved in the development and progression of several carcinomas. In breast cancer, NNMT was found to be overexpressed in several cell lines. However, the clinical relevance of NNMT in breast cancer is...

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Detalles Bibliográficos
Autores principales:	Wang, Yanzhong, Zeng, Jin, Wu, Weiping, Xie, Shuduo, Yu, Haitao, Li, Guoli, Zhu, Tao, Li, Fengying, Lu, Jie, Wang, Gavin Y., Xie, Xinyou, Zhang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525439/ https://www.ncbi.nlm.nih.gov/pubmed/31101119 http://dx.doi.org/10.1186/s13058-019-1150-z

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