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The LIM protein Ajuba/SP1 complex forms a feed forward loop to induce SP1 target genes and promote pancreatic cancer cell proliferation

BACKGROUND: The aim of this study is to explore the molecular mechanism of the LIM protein Ajuba and the transcription factor SP1 in the pathogenesis and progression of PDAC. Ajuba is a newly defined transcriptional co-regulator and plays important role in various cancer development, while SP1 is a...

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Detalles Bibliográficos
Autores principales:	Zhang, Bosen, Song, Liwei, Cai, Jiali, Li, Lei, Xu, Hong, Li, Mengying, Wang, Jiamin, Shi, Minmin, Chen, Hao, Jia, Hao, Hou, Zhaoyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525466/ https://www.ncbi.nlm.nih.gov/pubmed/31101117 http://dx.doi.org/10.1186/s13046-019-1203-2

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