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Protect, modify, deprotect (PMD): A strategy for creating vaccines to elicit antibodies targeting a specific epitope
In creating vaccines against infectious agents, there is often a desire to direct an immune response toward a particular conformational epitope on an antigen. We present a method, called protect, modify, deprotect (PMD), to generate immunogenic proteins aimed to direct a vaccine-induced antibody (Ab...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525525/ https://www.ncbi.nlm.nih.gov/pubmed/31028143 http://dx.doi.org/10.1073/pnas.1822062116 |