Cargando…
Targeting RIPK1 for the treatment of human diseases
RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide range of human neurodegenerative, autoimmune, and inflammatory diseases. This was supported by extensive studies which demonstrated that RIPK1 is a key mediator of apoptotic and necrotic cell death as well as infl...
Autores principales: | Degterev, Alexei, Ofengeim, Dimitry, Yuan, Junying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525537/ https://www.ncbi.nlm.nih.gov/pubmed/31048504 http://dx.doi.org/10.1073/pnas.1901179116 |
Ejemplares similares
-
Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target
por: Mifflin, Lauren, et al.
Publicado: (2020) -
Targeting RIPK1,2,3 to combat inflammation
por: Bullock, Alex N., et al.
Publicado: (2015) -
ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF
por: Muendlein, Hayley I., et al.
Publicado: (2022) -
RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
por: Zelic, Matija, et al.
Publicado: (2021) -
Targeting RIPK1 kinase for modulating inflammation in human diseases
por: Li, Wanjin, et al.
Publicado: (2023)