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Targeting RIPK1 for the treatment of human diseases

RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide range of human neurodegenerative, autoimmune, and inflammatory diseases. This was supported by extensive studies which demonstrated that RIPK1 is a key mediator of apoptotic and necrotic cell death as well as infl...

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Detalles Bibliográficos
Autores principales: Degterev, Alexei, Ofengeim, Dimitry, Yuan, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525537/
https://www.ncbi.nlm.nih.gov/pubmed/31048504
http://dx.doi.org/10.1073/pnas.1901179116

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