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Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo

Bacterial and fungal infections are a major cause of morbidity and mortality in neutropenic patients. Donor‐derived neutrophil transfusions have been used for prophylaxis or treatment for infection in neutropenic patients. However, the short half‐life and the limited availability of large numbers of...

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Detalles Bibliográficos
Autores principales: Trump, Lisa R., Nayak, Ramesh C., Singh, Abhishek K., Emberesh, Sana, Wellendorf, Ashley M., Lutzko, Carolyn M., Cancelas, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525559/
https://www.ncbi.nlm.nih.gov/pubmed/30793529
http://dx.doi.org/10.1002/sctm.18-0255