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Selective isotope labeling for NMR structure determination of proteins in complex with unlabeled ligands
The physiological role of proteins is frequently linked to interactions with non-protein ligands or posttranslational modifications. Structural characterization of these complexes or modified proteins by NMR may be difficult as the ligands are usually not available in an isotope-labeled form and NMR...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525670/ https://www.ncbi.nlm.nih.gov/pubmed/31041647 http://dx.doi.org/10.1007/s10858-019-00241-9 |