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Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell Reprogramming

Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) retain transcriptional memory, epigenetic memory, and metabolic memory from their somatic cells of origin and acquire aberrant characteristics distinct fr...

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Detalles Bibliográficos
Autores principales:	Spyrou, James, Gardner, David K., Harvey, Alexandra J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525803/ https://www.ncbi.nlm.nih.gov/pubmed/31191682 http://dx.doi.org/10.1155/2019/7360121

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