Morinda citrifolia and Its Active Principle Scopoletin Mitigate Protein Aggregation and Neuronal Apoptosis through Augmenting the DJ-1/Nrf2/ARE Signaling Pathway

Given the role of oxidative stress in PD pathogenesis and off-target side effects of currently available drugs, several natural phytochemicals seem to be promising in the management of PD. Here, we tested the hypothesis that scopoletin, an active principle obtained from Morinda citrifolia (MC), effi...

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Detalles Bibliográficos
Autores principales: Narasimhan, Kishore Kumar S., Jayakumar, Deepthy, Velusamy, Prema, Srinivasan, Ashokkumar, Mohan, Thangarajeswari, Ravi, Divya Bhavani, Uthamaraman, Saraswathi, Sathyamoorthy, Yogesh Kanna, Rajasekaran, Namakkal Soorappan, Periandavan, Kalaiselvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525839/
https://www.ncbi.nlm.nih.gov/pubmed/31191797
http://dx.doi.org/10.1155/2019/2761041

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