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p53-Mediated PI3K/AKT/mTOR Pathway Played a Role in Ptox(Dpt)-Induced EMT Inhibition in Liver Cancer Cell Lines

Epithelial-mesenchymal transition (EMT) involves metastasis and drug resistance; thus, a new EMT reversing agent is required. It has shown that wild-type p53 can reverse EMT back to epithelial characteristics, and iron chelator acting as a p53 inducer has been demonstrated. Moreover, recent study re...

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Detalles Bibliográficos
Autores principales:	Li, Yongli, Wang, Tingting, Sun, Yanjie, Huang, Tengfei, Li, Cuiping, Fu, Yun, Li, Yichun, Li, Changzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525883/ https://www.ncbi.nlm.nih.gov/pubmed/31191795 http://dx.doi.org/10.1155/2019/2531493

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