Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage

BACKGROUND: In osteoarthritis (OA), cartilage matrix is lost despite vigorous chondrocyte anabolism. In this study, we attempted to determine whether altered matrix synthesis is involved in this paradox in disease progression through gene expression analysis and ultrastructural analysis of collagen...

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Detalles Bibliográficos
Autores principales: Tanaka, Nobuho, Tashiro, Toshiyuki, Katsuragawa, Yozo, Sawabe, Motoji, Furukawa, Hiroshi, Fukui, Naoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525975/
https://www.ncbi.nlm.nih.gov/pubmed/31103042
http://dx.doi.org/10.1186/s12891-019-2596-y

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