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Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events in vivo
Background: Bioluminescence imaging (BLI) is one of the most widely used optical platforms in molecular imaging, but it suffers from severe tissue attenuation and autoluminescence in vivo. Methods: Here, we developed a novel BLI platform on the basis of bioluminescence resonance energy transfer (BRE...
Autores principales: | Nishihara, Ryo, Paulmurugan, Ramasamy, Nakajima, Takahiro, Yamamoto, Eiji, Natarajan, Arutselvan, Afjei, Rayhaneh, Hiruta, Yuki, Iwasawa, Naoko, Nishiyama, Shigeru, Citterio, Daniel, Sato, Moritoshi, Kim, Sung Bae, Suzuki, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525985/ https://www.ncbi.nlm.nih.gov/pubmed/31131059 http://dx.doi.org/10.7150/thno.32219 |
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