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EBV(LMP1)-induced metabolic reprogramming inhibits necroptosis through the hypermethylation of the RIP3 promoter

EBV infection is a recognized epigenetic driver of carcinogenesis. We previously showed that EBV could protect cancer cells from TNF-induced necroptosis. This study aims to explore the epigenetic mechanisms allowing cancer cells with EBV infection to escape from RIP3-dependent necroptosis. Methods:...

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Detalles Bibliográficos
Autores principales: Shi, Feng, Zhou, Min, Shang, Li, Du, Qianqian, Li, Yueshuo, Xie, Longlong, Liu, Xiaolan, Tang, Min, Luo, Xiangjian, Fan, Jia, Zhou, Jian, Gao, Qiang, Qiu, ShuangJian, Wu, Weizhong, Zhang, Xin, Bode, Ann M., Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525991/
https://www.ncbi.nlm.nih.gov/pubmed/31131045
http://dx.doi.org/10.7150/thno.30941