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Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice

Ryanodine receptor 2 (RyR2) plays an important role in maintaining the normal heart function, and mutantions can lead to arrhythmia, heart failure and other heart diseases. In this study, we successfully identified a piggyBac translocated RyR2 gene heterozygous mouse model (RyR2-PBmice) by tracking...

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Detalles Bibliográficos
Autores principales:	Wang, Qianqian, Wang, Chao, Wang, Bo, Shen, Qirui, Qiu, Leilei, Zou, Shuaijun, Wang, Tao, Liu, Guoyan, Wang, Beilei, Zhang, Liming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2019
Materias:	Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526016/ https://www.ncbi.nlm.nih.gov/pubmed/31143551 http://dx.doi.org/10.7717/peerj.6942

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