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Myocardial reconstruction in ischaemic cardiomyopathy
An increase in left ventricular volume after a myocardial infarction is a key component of the adverse remodelling process leading to chamber dysfunction, heart failure and an unfavourable outcome. Hence, the therapeutic strategies have been designed to reverse the remodelling process by medical the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526097/ https://www.ncbi.nlm.nih.gov/pubmed/31106339 http://dx.doi.org/10.1093/ejcts/ezy367 |
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author | Castelvecchio, Serenella Pappalardo, Omar Antonio Menicanti, Lorenzo |
author_facet | Castelvecchio, Serenella Pappalardo, Omar Antonio Menicanti, Lorenzo |
author_sort | Castelvecchio, Serenella |
collection | PubMed |
description | An increase in left ventricular volume after a myocardial infarction is a key component of the adverse remodelling process leading to chamber dysfunction, heart failure and an unfavourable outcome. Hence, the therapeutic strategies have been designed to reverse the remodelling process by medical therapy, devices or surgical strategies. Surgical ventricular reconstruction primarily combined with myocardial revascularization has been introduced as an optional intervention aimed to reduce the left ventricle through resection of the scar tissue and is recommended in selected patients with predominant heart failure symptoms, and with myocardial scarring and moderate left ventricular remodelling. This review outlines the rationale and the technique for reconstructing the left ventricle and the possible indications for using that technique, based on experiences from the centre with the largest international experience. The major contributions in the literature are briefly discussed. |
format | Online Article Text |
id | pubmed-6526097 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-65260972019-05-24 Myocardial reconstruction in ischaemic cardiomyopathy Castelvecchio, Serenella Pappalardo, Omar Antonio Menicanti, Lorenzo Eur J Cardiothorac Surg Reviews An increase in left ventricular volume after a myocardial infarction is a key component of the adverse remodelling process leading to chamber dysfunction, heart failure and an unfavourable outcome. Hence, the therapeutic strategies have been designed to reverse the remodelling process by medical therapy, devices or surgical strategies. Surgical ventricular reconstruction primarily combined with myocardial revascularization has been introduced as an optional intervention aimed to reduce the left ventricle through resection of the scar tissue and is recommended in selected patients with predominant heart failure symptoms, and with myocardial scarring and moderate left ventricular remodelling. This review outlines the rationale and the technique for reconstructing the left ventricle and the possible indications for using that technique, based on experiences from the centre with the largest international experience. The major contributions in the literature are briefly discussed. Oxford University Press 2019-06 2019-05-20 /pmc/articles/PMC6526097/ /pubmed/31106339 http://dx.doi.org/10.1093/ejcts/ezy367 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Reviews Castelvecchio, Serenella Pappalardo, Omar Antonio Menicanti, Lorenzo Myocardial reconstruction in ischaemic cardiomyopathy |
title | Myocardial reconstruction in ischaemic cardiomyopathy |
title_full | Myocardial reconstruction in ischaemic cardiomyopathy |
title_fullStr | Myocardial reconstruction in ischaemic cardiomyopathy |
title_full_unstemmed | Myocardial reconstruction in ischaemic cardiomyopathy |
title_short | Myocardial reconstruction in ischaemic cardiomyopathy |
title_sort | myocardial reconstruction in ischaemic cardiomyopathy |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526097/ https://www.ncbi.nlm.nih.gov/pubmed/31106339 http://dx.doi.org/10.1093/ejcts/ezy367 |
work_keys_str_mv | AT castelvecchioserenella myocardialreconstructioninischaemiccardiomyopathy AT pappalardoomarantonio myocardialreconstructioninischaemiccardiomyopathy AT menicantilorenzo myocardialreconstructioninischaemiccardiomyopathy |