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Factors predictive of high-output ileostomy: a retrospective single-center comparative study

PURPOSE: High-output syndrome (HOS) is a complication of ileostomy, which can affect quality of life significantly; however, its exact cause remains unknown. The aim of this study was to establish the frequency, as well as the preoperative and intraoperative factors predictive of HOS. METHODS: The s...

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Autores principales: Takeda, Mitsunobu, Takahashi, Hidekazu, Haraguchi, Naotsugu, Miyoshi, Norikatsu, Hata, Taishi, Yamamoto, Hirofumi, Matsuda, Chu, Mizushima, Tsunekazu, Doki, Yuichiro, Mori, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526144/
https://www.ncbi.nlm.nih.gov/pubmed/30594951
http://dx.doi.org/10.1007/s00595-018-1756-2
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author Takeda, Mitsunobu
Takahashi, Hidekazu
Haraguchi, Naotsugu
Miyoshi, Norikatsu
Hata, Taishi
Yamamoto, Hirofumi
Matsuda, Chu
Mizushima, Tsunekazu
Doki, Yuichiro
Mori, Masaki
author_facet Takeda, Mitsunobu
Takahashi, Hidekazu
Haraguchi, Naotsugu
Miyoshi, Norikatsu
Hata, Taishi
Yamamoto, Hirofumi
Matsuda, Chu
Mizushima, Tsunekazu
Doki, Yuichiro
Mori, Masaki
author_sort Takeda, Mitsunobu
collection PubMed
description PURPOSE: High-output syndrome (HOS) is a complication of ileostomy, which can affect quality of life significantly; however, its exact cause remains unknown. The aim of this study was to establish the frequency, as well as the preoperative and intraoperative factors predictive of HOS. METHODS: The subjects of this study were 164 consecutive patients who underwent colorectal cancer surgery with ileostomy construction at our institute between January, 2011 and August, 2018. Thirteen patients with postoperative complications reported as causes of HOS, including intraperitoneal abscess, paralytic ileus, and outlet obstruction, were excluded. We used a logistic regression analysis to identify the factors predictive of HOS. RESULTS: HOS developed in 36 of the 151 patients (23.8%). There were significantly more diabetic patients in the HOS group (P = 0.03), but other patient factors such as age, gender, body mass index, and use of daily laxatives were not significantly different between the groups. The HOS group had significantly more cases of total proctocolectomy (P = 0.04), but other surgical factors such as operative time, and blood transfusion were not significantly different between the two groups. CONCLUSIONS: These results indicate that diabetes and total proctocolectomy are preoperative predictors of HOS, allowing for the possibility of early intervention via post-surgical treatment.
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spelling pubmed-65261442019-06-05 Factors predictive of high-output ileostomy: a retrospective single-center comparative study Takeda, Mitsunobu Takahashi, Hidekazu Haraguchi, Naotsugu Miyoshi, Norikatsu Hata, Taishi Yamamoto, Hirofumi Matsuda, Chu Mizushima, Tsunekazu Doki, Yuichiro Mori, Masaki Surg Today Original Article PURPOSE: High-output syndrome (HOS) is a complication of ileostomy, which can affect quality of life significantly; however, its exact cause remains unknown. The aim of this study was to establish the frequency, as well as the preoperative and intraoperative factors predictive of HOS. METHODS: The subjects of this study were 164 consecutive patients who underwent colorectal cancer surgery with ileostomy construction at our institute between January, 2011 and August, 2018. Thirteen patients with postoperative complications reported as causes of HOS, including intraperitoneal abscess, paralytic ileus, and outlet obstruction, were excluded. We used a logistic regression analysis to identify the factors predictive of HOS. RESULTS: HOS developed in 36 of the 151 patients (23.8%). There were significantly more diabetic patients in the HOS group (P = 0.03), but other patient factors such as age, gender, body mass index, and use of daily laxatives were not significantly different between the groups. The HOS group had significantly more cases of total proctocolectomy (P = 0.04), but other surgical factors such as operative time, and blood transfusion were not significantly different between the two groups. CONCLUSIONS: These results indicate that diabetes and total proctocolectomy are preoperative predictors of HOS, allowing for the possibility of early intervention via post-surgical treatment. Springer Singapore 2018-12-29 2019 /pmc/articles/PMC6526144/ /pubmed/30594951 http://dx.doi.org/10.1007/s00595-018-1756-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Takeda, Mitsunobu
Takahashi, Hidekazu
Haraguchi, Naotsugu
Miyoshi, Norikatsu
Hata, Taishi
Yamamoto, Hirofumi
Matsuda, Chu
Mizushima, Tsunekazu
Doki, Yuichiro
Mori, Masaki
Factors predictive of high-output ileostomy: a retrospective single-center comparative study
title Factors predictive of high-output ileostomy: a retrospective single-center comparative study
title_full Factors predictive of high-output ileostomy: a retrospective single-center comparative study
title_fullStr Factors predictive of high-output ileostomy: a retrospective single-center comparative study
title_full_unstemmed Factors predictive of high-output ileostomy: a retrospective single-center comparative study
title_short Factors predictive of high-output ileostomy: a retrospective single-center comparative study
title_sort factors predictive of high-output ileostomy: a retrospective single-center comparative study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526144/
https://www.ncbi.nlm.nih.gov/pubmed/30594951
http://dx.doi.org/10.1007/s00595-018-1756-2
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