Cargando…
Role of T lymphocytes and papain enzymatic activity in the protection induced by the cysteine protease against Schistosoma mansoni in mice
Papain, an experimental model protease, was used to decipher the protective mechanism(s) of the cysteine peptidase-based schistosomiasis vaccine. To examine the role of T lymphocytes, athymic nude (nu/nu) and immunocompetent haired (nu/+) mice were subcutaneously (sc) injected with 50 µg active papa...
Autores principales: | Tallima, Hatem, Abou El Dahab, Marwa, El Ridi, Rashika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526234/ https://www.ncbi.nlm.nih.gov/pubmed/31193307 http://dx.doi.org/10.1016/j.jare.2018.12.008 |
Ejemplares similares
-
Specific Antibodies and Arachidonic Acid Mediate the Protection Induced by the Schistosoma mansoni Cysteine Peptidase-Based Vaccine in Mice
por: Tallima, Hatem, et al.
Publicado: (2020) -
Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase
por: Tallima, Hatem, et al.
Publicado: (2017) -
Increased hepatic interleukin-1, arachidonic acid, and reactive oxygen species mediate the protective potential of peptides shared by gut cysteine peptidases against Schistosoma mansoni infection in mice
por: Tallima, Hatem, et al.
Publicado: (2023) -
Induction of Protective Immune Responses Against Schistosomiasis haematobium in Hamsters and Mice Using Cysteine Peptidase-Based Vaccine
por: Tallima, Hatem, et al.
Publicado: (2015) -
Induction of protective immune responses against schistosomiasis using functionally active cysteine peptidases
por: El Ridi, Rashika, et al.
Publicado: (2014)