Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration

The retinal pigment epithelium (RPE) supports visual processing and photoreceptor homeostasis via energetically demanding cellular functions. Here, we describe the consequences of repressing peroxisome proliferator-activated receptor γ coactivator-1 α (PGC-1α), a master regulator of mitochondrial fu...

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Detalles Bibliográficos
Autores principales: Rosales, Mariana Aparecida Brunini, Shu, Daisy Y, Iacovelli, Jared, Saint-Geniez, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526284/
https://www.ncbi.nlm.nih.gov/pubmed/31101737
http://dx.doi.org/10.26508/lsa.201800212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526284/
https://www.ncbi.nlm.nih.gov/pubmed/31101737
http://dx.doi.org/10.26508/lsa.201800212

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