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Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils

α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central nervous system (CNS) inoculation studies using either in vitro polymerized αS fibrils or in vivo derived lysates containing αS aggregates...

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Detalles Bibliográficos
Autores principales:	Dhillon, Jess-Karan S., Trejo-Lopez, Jorge A., Riffe, Cara, Levites, Yona, Sacino, Amanda N., Borchelt, David R., Yachnis, Anthony Y., Giasson, Benoit I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526622/ https://www.ncbi.nlm.nih.gov/pubmed/31109378 http://dx.doi.org/10.1186/s40478-019-0733-3

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