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Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR
Macroautophagy/autophagy dysfunction is associated with many neurodegenerative diseases. TFEB (transcription factor EB), an important molecule that regulates lysosomal and autophagy function, is regarded as a potential target for treating some neurodegenerative diseases. However, the relationship be...
Autores principales: | Ye, Bin, Wang, Quan, Hu, Haixia, Shen, Yilin, Fan, Cui, Chen, Penghui, Ma, Yan, Wu, Hao, Xiang, Mingliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526833/ https://www.ncbi.nlm.nih.gov/pubmed/30706760 http://dx.doi.org/10.1080/15548627.2019.1569926 |
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