Cargando…
TRIM59 deficiency curtails breast cancer metastasis through SQSTM1-selective autophagic degradation of PDCD10
Receptor-driven selective macroautophagy/autophagy delivers ubiquitinated targets for autophagosomal clearance to maintain metabolic homeostasis and orchestrate reparative inflammatory responses. Deregulated autophagy is linked to tumor progression, but the exact mechanisms of selective autophagy in...
Autores principales: | Tan, Peng, He, Lian, Zhou, Yubin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526857/ https://www.ncbi.nlm.nih.gov/pubmed/30653426 http://dx.doi.org/10.1080/15548627.2019.1569951 |
Ejemplares similares
-
TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10
por: Tan, Peng, et al.
Publicado: (2018) -
Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy
por: Manirujjaman, M., et al.
Publicado: (2020) -
Phasing out the bad—How SQSTM1/p62 sequesters ubiquitinated proteins for degradation by autophagy
por: Zaffagnini, Gabriele, et al.
Publicado: (2018) -
TRIM29 mediates lung squamous cell carcinoma cell metastasis by regulating autophagic degradation of E-cadherin
por: Xu, Weifeng, et al.
Publicado: (2020) -
TRIM72-mediated degradation of the short form of p62/SQSTM1 rheostatically controls selective autophagy in human cells
por: Wang, Cheng-Cheng, et al.
Publicado: (2022)