Cargando…

Quick synthesis of a novel combinatorial delivery system of siRNA and doxorubicin for a synergistic anticancer effect

Purpose: Combining siRNA and other chemotherapeutic agents into one nanocarrier can overcome the multidrug resistance (MDR) phenomenon by synergistically MDR relative genes silencing and elevated chemotherapeutic activity. Most of these systems are typically fabricated through complicated procedures...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Mengchun, Wang, Ledan, Wang, Fang, Li, Fan, Xia, Weiliang, Gu, Hongchen, Chen, Yijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526930/ https://www.ncbi.nlm.nih.gov/pubmed/31190812 http://dx.doi.org/10.2147/IJN.S198511

Ejemplares similares

Synergistic treatment of osteosarcoma with biomimetic nanoparticles transporting doxorubicin and siRNA
por: Zhao, Jingtong, et al.
Publicado: (2023)

AGO-accessible anticancer siRNAs designed with synergistic miRNA-like activity
por: Gu, Dowoon, et al.
Publicado: (2021)

Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes
por: Egorova, Anna A., et al.
Publicado: (2019)

Novel polymer micelle mediated co-delivery of doxorubicin and P-glycoprotein siRNA for reversal of multidrug resistance and synergistic tumor therapy
por: Zhang, Chun-ge, et al.
Publicado: (2016)

PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery
por: Zhao, Yi, et al.
Publicado: (2016)

siRNA Knockdown of RRM2 Effectively Suppressed Pancreatic Tumor Growth Alone or Synergistically with Doxorubicin
por: Zheng, Shuquan, et al.
Publicado: (2018)

Peptide Nanoparticle-Mediated Combinatorial Delivery of Cancer-Related siRNAs for Synergistic Anti-Proliferative Activity in Triple Negative Breast Cancer Cells
por: Egorova, Anna, et al.
Publicado: (2021)

Galactosylated Liposomes for Targeted Co-Delivery of Doxorubicin/Vimentin siRNA to Hepatocellular Carcinoma
por: Oh, Hea Ry, et al.
Publicado: (2016)

Inhibition of cell proliferation through an ATP-responsive co-delivery system of doxorubicin and Bcl-2 siRNA
por: Zhang, Jianxu, et al.
Publicado: (2017)

Highly effective antiangiogenesis via magnetic mesoporous silica-based siRNA vehicle targeting the VEGF gene for orthotopic ovarian cancer therapy
por: Chen, Yijie, et al.
Publicado: (2015)

Codelivery of doxorubicin and MDR1-siRNA by mesoporous silica nanoparticles-polymerpolyethylenimine to improve oral squamous carcinoma treatment
por: Wang, Dandan, et al.
Publicado: (2017)

Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy
por: Xia, Yu, et al.
Publicado: (2017)

Polyethylenimine-Conjugated Hydroxyethyl Cellulose for Doxorubicin/Bcl-2 siRNA Co-Delivery Systems
por: Park, Jiwon, et al.
Publicado: (2023)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Lipopolyplex-Mediated Co-Delivery of Doxorubicin and FAK siRNA to Enhance Therapeutic Efficiency of Treating Colorectal Cancer
por: Debele, Tilahun Ayane, et al.
Publicado: (2023)

Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy
por: Butowska, Kamila, et al.
Publicado: (2023)

Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies
por: Chen, Mengchun, et al.
Publicado: (2020)

High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA
por: Ye, Junxiao, et al.
Publicado: (2017)

Redox/pH-Responsive 2-in-1 Chimeric Nanoparticles for the Co-Delivery of Doxorubicin and siRNA
por: Wu, Hsi-Chin, et al.
Publicado: (2021)

Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer
por: Pan, Di, et al.
Publicado: (2021)

Advances in Lipid Nanoparticles for siRNA Delivery
por: Tam, Yuen Yi C., et al.
Publicado: (2013)

pH-sensitive CAP/SiO(2) composite for efficient co-delivery of doxorubicin and siRNA to overcome multiple drug resistance
por: Cai, Zheng, et al.
Publicado: (2020)

Non-viral siRNA delivery to the lung()
por: Thomas, Mini, et al.
Publicado: (2007)

Polymeric Core–Shell Combinatorial Nanomedicine for Synergistic Anticancer Therapy
por: Shanavas, Asifkhan, et al.
Publicado: (2019)

Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications
por: Gangopadhyay, Sumit, et al.
Publicado: (2022)

Enhanced anticancer effect of doxorubicin by TPGS-coated liposomes with Bcl-2 siRNA-corona for dual suppression of drug resistance
por: Li, Yinghuan, et al.
Publicado: (2020)

Aptamer mediated siRNA delivery
por: Chu, Ted C., et al.
Publicado: (2006)

Pulmonary delivery of therapeutic siRNA
por: Lam, Jenny Ka-Wing, et al.
Publicado: (2012)

Intranasal Delivery of Antiviral siRNA
por: Barik, Sailen
Publicado: (2010)

Drug Delivery of siRNA Therapeutics
por: Lamberti, Gaetano, et al.
Publicado: (2020)

Doxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo
por: Sun, Qi, et al.
Publicado: (2018)

Glycol chitosan nanoparticles as specialized cancer therapeutic vehicles: Sequential delivery of doxorubicin and Bcl-2 siRNA
por: Yoon, Hong Yeol, et al.
Publicado: (2014)

Effective combination treatment of lung cancer cells by single vehicular delivery of siRNA and different anticancer drugs
por: Li, Jinming, et al.
Publicado: (2016)

A Light-Driven Therapy of Pancreatic Adenocarcinoma Using Gold Nanorods-Based Nanocarriers for Co-Delivery of Doxorubicin and siRNA
por: Yin, Feng, et al.
Publicado: (2015)

Synthesis of Polymer-Lipid Nanoparticles by Microfluidic Focusing for siRNA Delivery
por: Li, Yujing, et al.
Publicado: (2016)

Transdermal Delivery of siRNA through Microneedle Array
por: Deng, Yan, et al.
Publicado: (2016)

Bone site-specific delivery of siRNA
por: Liu, Xinli
Publicado: (2016)

Chaperonin–Dendrimer Conjugates for siRNA Delivery
por: Nussbaumer, Martin G., et al.
Publicado: (2016)

Amphiphilic Peptides for Efficient siRNA Delivery
por: Mozaffari, Saghar, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c1d3u74tccp0hmbr2bn84r9dhi