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A Platform for the Discovery of New Macrolide Antibiotics
The chemical modification of structurally complex fermentation products, a process known as semisynthesis, has been an important tool for the discovery and manufacture of antibiotics for the treatment of various infectious diseases. However, many of the therapeutics obtained in this way are no longe...
Autores principales: | Seiple, Ian B., Zhang, Ziyang, Jakubec, Pavol, Langlois-Mercier, Audrey, Wright, Peter M., Hog, Daniel T., Yabu, Kazuo, Allu, Senkara Rao, Fukuzaki, Takehiro, Carlsen, Peter N., Kitamura, Yoshiaki, Zhou, Xiang, Condakes, Matthew L., Szczypiński, Filip T., Green, William D., Myers, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526944/ https://www.ncbi.nlm.nih.gov/pubmed/27193679 http://dx.doi.org/10.1038/nature17967 |
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