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Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men

OBJECTIVE: Hair whitening (HW) is strongly linked with aging. Ascending aortic dilation (AAD) and HW share common etiologic factors. We investigated the association of HW with ascending aortic diameters. METHODS: Our study included 93 male subjects aged below 50 years. All patients underwent echocar...

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Autores principales: Cetin, Mustafa, Bozbeyoglu, Emrah, Erdogan, Turan, Kocaman, Sinan Altan, Satiroglu, Omer, Durakoglugil, Murtaza Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526979/
https://www.ncbi.nlm.nih.gov/pubmed/31180373
http://dx.doi.org/10.14744/nci.2017.43433
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author Cetin, Mustafa
Bozbeyoglu, Emrah
Erdogan, Turan
Kocaman, Sinan Altan
Satiroglu, Omer
Durakoglugil, Murtaza Emre
author_facet Cetin, Mustafa
Bozbeyoglu, Emrah
Erdogan, Turan
Kocaman, Sinan Altan
Satiroglu, Omer
Durakoglugil, Murtaza Emre
author_sort Cetin, Mustafa
collection PubMed
description OBJECTIVE: Hair whitening (HW) is strongly linked with aging. Ascending aortic dilation (AAD) and HW share common etiologic factors. We investigated the association of HW with ascending aortic diameters. METHODS: Our study included 93 male subjects aged below 50 years. All patients underwent echocardiography to measure ascending aortic diameter, in addition to routine biochemistry tests, physical examination, and thorough medical history. HW score (HWS) was defined according to the percentage of white hair (HWS 1: <25%; HWS 2: 25–50%; HWS 3: 50–75%; and HWS 4: 75–100). RESULTS: Patients with highest HWS were older and had a higher percentage of hypertension (HT) and family history of HW. Moreover, this subgroup had increased ascending aortic diameter, higher serum uric acid, and lower total bilirubin concentrations. Multivariate analyses including age, HT, height, waist circumference, c-reactive protein, and family history of HW identified body weight and HWS as the independent predictors of ascending aortic diameter. CONCLUSION: An independent association between the degree of HW and AAD exists in middle-aged men, which may depend on coexisting factors that enhance both pathologies rather than causality. We think that oxidative stress may be one of these stressors.
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spelling pubmed-65269792019-06-06 Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men Cetin, Mustafa Bozbeyoglu, Emrah Erdogan, Turan Kocaman, Sinan Altan Satiroglu, Omer Durakoglugil, Murtaza Emre North Clin Istanb Original Article OBJECTIVE: Hair whitening (HW) is strongly linked with aging. Ascending aortic dilation (AAD) and HW share common etiologic factors. We investigated the association of HW with ascending aortic diameters. METHODS: Our study included 93 male subjects aged below 50 years. All patients underwent echocardiography to measure ascending aortic diameter, in addition to routine biochemistry tests, physical examination, and thorough medical history. HW score (HWS) was defined according to the percentage of white hair (HWS 1: <25%; HWS 2: 25–50%; HWS 3: 50–75%; and HWS 4: 75–100). RESULTS: Patients with highest HWS were older and had a higher percentage of hypertension (HT) and family history of HW. Moreover, this subgroup had increased ascending aortic diameter, higher serum uric acid, and lower total bilirubin concentrations. Multivariate analyses including age, HT, height, waist circumference, c-reactive protein, and family history of HW identified body weight and HWS as the independent predictors of ascending aortic diameter. CONCLUSION: An independent association between the degree of HW and AAD exists in middle-aged men, which may depend on coexisting factors that enhance both pathologies rather than causality. We think that oxidative stress may be one of these stressors. Kare Publishing 2018-08-07 /pmc/articles/PMC6526979/ /pubmed/31180373 http://dx.doi.org/10.14744/nci.2017.43433 Text en Copyright: © 2019 by Istanbul Northern Anatolian Association of Public Hospitals http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Original Article
Cetin, Mustafa
Bozbeyoglu, Emrah
Erdogan, Turan
Kocaman, Sinan Altan
Satiroglu, Omer
Durakoglugil, Murtaza Emre
Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
title Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
title_full Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
title_fullStr Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
title_full_unstemmed Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
title_short Hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
title_sort hair whitening and obesity are independently related to ascending aorta dilatation in young-middle aged men
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526979/
https://www.ncbi.nlm.nih.gov/pubmed/31180373
http://dx.doi.org/10.14744/nci.2017.43433
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