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Proteomic discovery of substrates of the cardiovascular protease ADAMTS7

The protease ADAMTS7 functions in the extracellular matrix (ECM) of the cardiovascular system. However, its physiological substrate specificity and mechanism of regulation remain to be explored. To address this, we conducted an unbiased substrate analysis using terminal amine isotopic labeling of su...

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Detalles Bibliográficos
Autores principales:	Colige, Alain, Monseur, Christine, Crawley, James T. B., Santamaria, Salvatore, de Groot, Rens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527163/ https://www.ncbi.nlm.nih.gov/pubmed/30926607 http://dx.doi.org/10.1074/jbc.RA119.007492

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