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Chronic pain in adults with sickle cell disease is associated with alterations in functional connectivity of the brain

Chronic pain affects 50% of adults with sickle cell disease (SCD). Although central sensitization is thought to contribute to the pathogenesis of this chronic pain, no studies have examined differences in functional connectivity of the brain between patients with SCD with and without chronic pain. W...

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Detalles Bibliográficos
Autores principales: Karafin, Matthew S., Chen, Guangyu, Wandersee, Nancy J., Brandow, Amanda M., Hurley, Robert W., Simpson, Pippa, Ward, Doug, Li, Shi-Jiang, Field, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527293/
https://www.ncbi.nlm.nih.gov/pubmed/31107926
http://dx.doi.org/10.1371/journal.pone.0216994