Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma

Mast cells (MC) have been identified in human lung adenocarcinoma (LADC) tissues, but their functional role has not been investigated in vivo. For this, we applied three mouse models of KRAS-mutant LADC to two different MC-deficient mouse strains (cKit(Wsh) and Cpa3.Cre). Moreover, we derived MC gen...

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Detalles Bibliográficos
Autores principales: Lilis, Ioannis, Ntaliarda, Giannoula, Papaleonidopoulos, Vassilios, Giotopoulou, Georgia A, Oplopoiou, Maria, Marazioti, Antonia, Spella, Magda, Marwitz, Sebastian, Goldmann, Torsten, Bravou, Vasiliki, Giopanou, Ioanna, Stathopoulos, Georgios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527299/
https://www.ncbi.nlm.nih.gov/pubmed/31143511
http://dx.doi.org/10.1080/2162402X.2019.1593802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527299/
https://www.ncbi.nlm.nih.gov/pubmed/31143511
http://dx.doi.org/10.1080/2162402X.2019.1593802

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