Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin

The function of small G protein signalling modulators (SGSM1/2/3) in cancer remains unknown. Our findings demonstrated that SGSM2 is a plasma membrane protein that strongly interacted with E-cadherin/β-catenin. SGSM2 downregulation enhanced the phosphorylation of focal adhesion kinase (FAK; Y576/577...

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Detalles Bibliográficos
Autores principales: Lin, Juo-Han, Lee, Wen-Jui, Wu, Han-Chung, Wu, Chih-Hsiung, Chen, Li-Ching, Huang, Chi-Cheng, Chang, Hang-Lung, Cheng, Tzu-Chun, Chang, Hui-Wen, Ho, Chi-Tang, Tu, Shih-Hsin, Ho, Yuan-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527379/
https://www.ncbi.nlm.nih.gov/pubmed/30744493
http://dx.doi.org/10.1080/19336918.2019.1568139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527379/
https://www.ncbi.nlm.nih.gov/pubmed/30744493
http://dx.doi.org/10.1080/19336918.2019.1568139

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