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Control of mRNA Splicing by Intragenic RNA Activators of Stress Signaling: Potential Implications for Human Disease
A critical step in the cellular stress response is transient activation of the RNA-dependent protein kinase PKR by double-helical RNA, resulting in down-regulation of protein synthesis through phosphorylation of the α chain of translation initiation factor eIF2, a major PKR substrate. However, intra...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527590/ https://www.ncbi.nlm.nih.gov/pubmed/31139209 http://dx.doi.org/10.3389/fgene.2019.00464 |