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Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes

The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg(2+) block and lack of desensitization. Recent studies have highlighted the unique contribution of GluN2C and GluN2D subunits in various aspects...

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Detalles Bibliográficos
Autores principales: Shelkar, Gajanan P., Pavuluri, Ratnamala, Gandhi, Pauravi J., Ravikrishnan, Aparna, Gawande, Dinesh Y., Liu, Jinxu, Stairs, Dustin J., Ugale, Rajesh R., Dravid, Shashank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527682/
https://www.ncbi.nlm.nih.gov/pubmed/31110197
http://dx.doi.org/10.1038/s41598-019-43957-2