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Precipitation of complex antibody solutions: influence of contaminant composition and cell culture medium on the precipitation behavior
Preparative protein precipitation is known as a cost-efficient and easy-to-use alternative to chromatographic purification steps. This said, at the moment, there is no process for monoclonal antibodies (mAb) on the market, although especially polyethylene glycol-induced precipitation has shown great...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527789/ https://www.ncbi.nlm.nih.gov/pubmed/30887102 http://dx.doi.org/10.1007/s00449-019-02103-y |