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In vitro degradation of β-amyloid fibrils by microbial keratinase

INTRODUCTION: Amyloid fibrils are misfolded, protease-resistant forms of normal proteins. They are infectious such as prions or noninfectious such as β-amyloid (Aβ) fibrils causing Alzheimer's disease (AD). Prions and amyloids are structurally similar, possessing cross β-pleated sheet-like stru...

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Detalles Bibliográficos
Autores principales: Ningthoujam, Debananda S., Mukherjee, Saikat, Devi, Laishram Jaya, Singh, Elangbam Shanta, Tamreihao, Keishing, Khunjamayum, Rakhi, Banerjee, Sumita, Mukhopadhyay, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527806/
https://www.ncbi.nlm.nih.gov/pubmed/31193333
http://dx.doi.org/10.1016/j.trci.2019.03.003