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FABP1 controls hepatic transport and biotransformation of Δ(9)-THC
The increasing use of medical marijuana highlights the importance of developing a better understanding of cannabinoid metabolism. Phytocannabinoids, including ∆(9)-tetrahydrocannabinol (THC), are metabolized and inactivated by cytochrome P450 enzymes primarily within the liver. The lipophilic nature...
Autores principales: | Elmes, Matthew W., Prentis, Lauren E., McGoldrick, Luke L., Giuliano, Christopher J., Sweeney, Joseph M., Joseph, Olivia M., Che, Joyce, Carbonetti, Gregory S., Studholme, Keith, Deutsch, Dale G., Rizzo, Robert C., Glynn, Steven E., Kaczocha, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527858/ https://www.ncbi.nlm.nih.gov/pubmed/31110286 http://dx.doi.org/10.1038/s41598-019-44108-3 |
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