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A Role for Chromatin Remodeling in Cohesin Loading onto Chromosomes

Cohesin is a conserved, ring-shaped protein complex that topologically embraces DNA. Its central role in genome organization includes functions in sister chromatid cohesion, DNA repair, and transcriptional regulation. Cohesin loading onto chromosomes requires the Scc2-Scc4 cohesin loader, whose pres...

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Detalles Bibliográficos
Autores principales: Muñoz, Sofía, Minamino, Masashi, Casas-Delucchi, Corella S., Patel, Harshil, Uhlmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527865/
https://www.ncbi.nlm.nih.gov/pubmed/30922844
http://dx.doi.org/10.1016/j.molcel.2019.02.027