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Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

Lymphatic vasculature is crucial for metastasis in triple-negative breast cancer (TNBC); however, cellular and molecular drivers controlling lymphovascular metastasis are poorly understood. We define a macrophage-dependent signaling cascade that facilitates metastasis through lymphovascular remodeli...

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Detalles Bibliográficos
Autores principales: Evans, Rachel, Flores-Borja, Fabian, Nassiri, Sina, Miranda, Elena, Lawler, Katherine, Grigoriadis, Anita, Monypenny, James, Gillet, Cheryl, Owen, Julie, Gordon, Peter, Male, Victoria, Cheung, Anthony, Noor, Farzana, Barber, Paul, Marlow, Rebecca, Francesch-Domenech, Erika, Fruhwirth, Gilbert, Squadrito, Mario, Vojnovic, Borivoj, Tutt, Andrew, Festy, Frederic, De Palma, Michele, Ng, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527923/
https://www.ncbi.nlm.nih.gov/pubmed/31091437
http://dx.doi.org/10.1016/j.celrep.2019.04.076